Report Overview

Global Artificial Cornea and Corneal Implant Market - Industry Trends & Forecast Report 2028

Global Artificial Cornea and Corneal Implant Market size was worth USD 397.5 million in 2021 and is projected to reach USD 863.7 million by 2028, recording growth at a CAGR of 12% during the forecast period (2022-2028). The rapid expansion of the market is due to the rise in ophthalmic illnesses, such as keratoconus, Fuchs dystrophy, and viral keratitis; and consumers' willingness to spend more on their eye care. Aging global population; growing number of surgical procedures across the world, including in the most populous emerging economies (China and India); and the spurring demand for innovative treatment methods are also expected to be major growth factors for global artificial cornea and corneal implant market during the period in analysis.

Artificial Cornea and Corneal Implant - Overview

This technique involves either repairing a specific layer of the cornea with one of several sutureless techniques or suturing healthy cornea tissue from a donor's eye to replace the damaged one. Rejection can cause corneal transplants to fail, and in certain situations, they may produce unsatisfactory results. In a cornea transplant, the diseased cornea is removed whole or part and is replaced with healthy donor tissue. A corneal graft or keratoplasty is another name for a cornea transplant. It can be used to cure serious infections or damage while also enhancing vision and reducing pain.

Global Artificial Cornea and Corneal Implant Market Forecast and Trends

Growth Drivers

Eye Illnesses are Becoming More Common

Globally, the number of people suffering from serious eye disorders is increasing, and vision loss is becoming a major public health concern. The increasing incidence of chronic diseases such as diabetes and hypertension, as well as the aging population, have increased the prevalence of eye diseases such as diabetic retinopathy and ocular hypertension (glaucoma). The number of people who are blind or have low vision is also expected to rise significantly. According to the Royal National Institute of Blind People (RNIB), over 2 million people in the UK suffered from a visual loss in 2013, with this figure anticipated to rise to 4.1 million by 2050. There are currently 146 million trachoma patients worldwide, of whom 10 million have trichiasis and require surgery to avert corneal blindness, and 4.9 million have trachomatous corneal scarring that has rendered them entirely blind.

Growing Rates of Corneal Blindness and Shortage of Cornea Donors

On a global scale, 10 million people suffer from corneal blindness. The rising prevalence of corneal blindness is therefore a key element driving the growth of artificial cornea implants. The market has grown quickly in part due to the shortage of human cornea donors. Additionally, if there are more trauma instances, there is a higher chance of eye injury, which will propel the industry forward. A human donor cornea transplant has a low likelihood of nerve regeneration, whereas a biosynthetic cornea implant has a high likelihood of nerve regeneration after implantation. Patients with corneal blindness must wait a very long period for corneal transplants in densely populated areas like India because there aren't many cornea donors available. Due to corneal abnormalities, 6.8 million people in the nation have impaired vision in one eye, while 1 million people have poor vision in both eyes.

Insufficient Corneal Donors

Since roughly 10 million individuals worldwide require corneal transplants, there is a critical demand for corneal donors. There is a more than six-month waiting list for corneal transplants among individuals with corneal blindness in densely populated nations like India due to a severe shortage of donor corneas. Due to corneal conditions, 6.8 million people in the nation have impaired vision in one eye and about 1 million have poor vision in both eyes. It was predicted that 10.6 million cases of unilateral corneal blindness would exist in India by the end of 2020. About 120,000 persons experienced corneal blindness in 2019. Every year, the nation requires about 250,000 corneas, but only about 25,000 corneas are donated nationwide. Manufacturers of corneal implants should benefit from substantial growth potential given the high burden of corneal blindness and the dearth of corneal donors.

 Restraints

High Price of Ophthalmology Equipment and Surgeries

The creation of femtosecond lasers and other technological developments in ophthalmic lasers have shortened operating times, enhanced operative outcomes, and increased patient convenience. The exorbitant price of this equipment, however, is anticipated to impede their expansion. The Singapore Eye Research Institute (SERI) conducted a study that determined the price of a femtosecond laser to be between USD 400,000 and USD 550,000. This has an impact on how widely they are used by end users because it is hard to predict how many patients will select femtosecond laser therapy over more traditional treatments and whether this will generate enough revenue to pay for the laser's installation. The price of a new fundus machine ranges from $15,000 to 60,000 dollars, and an OCT costs between 70,000 and 120,000 dollars. All these factors hinder market growth.

Impact of COVID-19 on Global Artificial Cornea and Corneal Implant Market

Due to lockdowns and other restrictions put in place to stop the COVID-19 epidemic, there has been a considerable decrease in the number of patient visits to clinics in the first and second quarters of 2020. As a result, fewer elective eye procedures were performed each week in hospitals and clinics during that time. The number of elective procedures has decreased from 200 surgeries per week to just ten surgeries per week, according to the Ophthalmology Times story. Additionally, the frequency of patient appointments to examination centers has been canceled by 15% in nations like the US. The coronavirus disease (COVID-19) pandemic caused a large loss in patient volume for ophthalmology, according to the same publication. According to estimates, the number of patients seeking glaucoma treatment decreased by 88% and those seeking cataract surgery by 97%. Government programs assisted numerous practices during this time, including Paycheck Protection Program loans, which enabled the ophthalmology sector to successfully continue operations.

Global Artificial Cornea and Corneal Implant Market - By Type

Based on the type, the Global Artificial Cornea and Corneal Implant Market are segmented into Human Cornea and Artificial Cornea. The human cornea segment is likely to maintain its dominance during the forecast period, owing to increased awareness of corneal transplantation and eye tissue donations, particularly in developing economies. Furthermore, the penetrating keratoplasty segment led the artificial cornea and corneal implant market in 2019 due to its use in the treatment of various corneal diseases such as keratoconus, bullous keratopathy, and dystrophies. This is anticipated to increase segment growth. All these factors propel the growth of the Global Artificial Cornea and Corneal Implant Market during a forecast period (2022-2028).

Global Artificial Cornea and Corneal Implant Market – By Transplant Type

Based on transplant type, the Global Artificial Cornea and Corneal Implant Market are segmented into Penetrating Keratoplasty, and Endothelial Keratoplasty. The penetrating keratoplasty category holds the highest proportion of the worldwide artificial cornea and corneal implants market in 2020. The increased number of people suffering from eye problems such as infectious keratitis and eyeball injury can be ascribed to the large share of this category. All these factors boost the growth of the Global Artificial Cornea and Corneal Implant Market during the forecast period (2022-2028).

Global Artificial Cornea and Corneal Implant Market - By Disease Indication

Based on disease indication, the Global Artificial Cornea and Corneal Implant Market are segmented into Fuch’s Dystrophy, Fungal Keratitis, Keratoconus, and Others. The sector for Fuchs' dystrophy is anticipated to expand at the fastest rate during the projection period. The main drivers of this segment's growth are the increasing prevalence of the condition and the general increase in public awareness regarding early disease diagnosis.

Global Artificial Cornea and Corneal Implant Market - By Region

Geographically, the Global Artificial Cornea and Corneal Implant Market are segmented into North America, Europe, The Asia Pacific, Latin America, and The Middle East and Africa. The artificial cornea and corneal implant market in the world were dominated by North America. In North America, the market is well-established, and the US dominates it there. The significant market share of North America is primarily explained by the region's developed healthcare infrastructure, increased adoption of sophisticated healthcare technology, higher spending power among end users of ophthalmic equipment, and a sizable number of corneal implant producers.

Competitive Landscape

The leading market players in the Global Artificial Cornea and Corneal Implant Market are AJL Ophthalmic, CorneaGen Inc, Addition Technology Inc, LinkoCare Life Science AB, Presbia Plc, Mediphacos, Aurolab, Cornea Biosciences, Dioptex GmbH, EyeYon Medical, Massachusetts Eye and Ear, Florida Lions Eye Bank, and other prominent players.

The Global Artificial Cornea and Corneal Implant Market is highly fragmented with the presence of several manufacturing companies in the country. The market leaders retain their supremacy by spending on research and development, incorporating cutting-edge technology into their goods, and releasing upgraded items for customers. Various tactics, including strategic alliances, agreements, mergers, and partnerships, are used.

Recent Development

• In June 2020, AJL Ophthalmic (Spain) received CE Mark approval for ENDO-K PRO. Product approval will enable the company to provide its portfolio to end users.

Scope of the Report

By Type

• Human Cornea

• Artificial Cornea

By Transplant Type

• Penetrating Keratoplasty

• Endothelial Keratoplasty

By Disease Indication

• Fuch’s Dystrophy

• Fungal Keratitis

• Keratoconus

• Others

By End-User

• Hospitals

• Specialty Clinics

• Ambulatory Surgical Centers

• Others

By Region

• North America

• Europe

• Asia Pacific

• Latin America

• Middle East and Africa

1. Research Framework
   1. Research Objective
   2. Transplant Type Overview
   3. Market Segmentation
2. Research Methodology
   1. Qualitative Research
      1. Primary & Secondary Research
   2. Quantitative Research
   3. Market Breakdown & Data Triangulation
      1. Secondary Research
      2. Primary Research
   4. Breakdown of Primary Research Respondents
   5. Assumption & Limitation
3. Executive Summary
4. Global Artificial Cornea and Corneal Implant Market Insights
   1. Industry Value Chain Analysis
   2. DROC Analysis
      1. Growth Drivers
      2. Restraints
      3. Opportunities
      4. Challenges
   3. Technological Advancement/Recent Development
   4. Regulatory Framework
   5. Porter’s Five Forces Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of New Entrants
      4. Threat of Substitutes
      5. Intensity of Rivalry
5. Global Artificial Cornea and Corneal Implant Market Overview
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Type
         1. Human Cornea
         2. Artificial Cornea
      2. By Transplant Type
         1. Penetrating Keratoplasty
         2. Endothelial Keratoplasty
      3. By Disease Indication
         1. Fuch’s Dystrophy
         2. Fungal Keratitis
         3. Keratoconus
         4. Others
      4. By End-User
         1. Hospitals
         2. Specialty Clinics
         3. Ambulatory Surgical Centers
         4. Others
      5. By Region
         1. North America
         2. Europe
         3. The Asia Pacific
         4. Latin America
         5. The Middle East and Africa
6. North America Artificial Cornea and Corneal Implant Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Type
      2. By Transplant Type
      3. By Disease Indication
      4. By End-User
      5. By Country
         1. United Type
         2. Canada
7. Europe Artificial Cornea and Corneal Implant Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Type
      2. By Transplant Type
      3. By Disease Indication
      4. By End-User
      5. By Country
         1. Germany
         2. United Kingdom
         3. Italy
         4. France
         5. Spain
         6. Rest of Europe
8. The Asia Pacific Artificial Cornea and Corneal Implant Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Type
      2. By Transplant Type
      3. By Disease Indication
      4. By End-User
      5. By Country
         1. China
         2. India
         3. Japan
         4. South Korea
         5. Rest of Asia Pacific
9. Latin America Artificial Cornea and Corneal Implant Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Type
      2. By Transplant Type
      3. By Disease Indication
      4. By End-User
      5. By Country
         1. Brazil
         2. Mexico
         3. Rest of Latin America
10. The Middle East & Africa Artificial Cornea and Corneal Implant Market
    1. Market Size & Forecast by Value, 2018-2028
       1. By Value (USD Million)
    2. Market Share & Forecast
       1. By Type
       2. By Transplant Type
       3. By Disease Indication
       4. By End-User
       5. By Country
          1. Saudi Arabia
          2. UAE
          3. South Africa
          4. Rest of the Middle East & Africa
11. Competitive Landscape
    1. List of Key Players and Their Offerings
    2. Market Share Analysis, 2021
    3. Competitive Benchmarking, By Operating Parameters
    4. Key Strategic Development (Mergers, Acquisitions, Partnerships, etc.)
12. Impact of Covid-19 on Global Artificial Cornea and Corneal Implant Market
13. Company Profile (Company Overview, Financial Matrix, Competitive Landscape, Key Personnel, Key Competitors, Contact Address, and Strategic Outlook) **
    1. AJL Ophthalmic
    2. CorneaGen Inc
    3. Addition Technology Inc
    4. LinkoCare Life Science AB
    5. Presbia Plc
    6. Mediphacos
    7. Aurolab
    8. Cornea Biosciences
    9. Dioptex GmbH
    10. EyeYon Medical
    11. Massachusetts Eye and Ear
    12. Florida Lions Eye Bank
    13. Other Prominent Players
14. Key Strategic Recommendations

*Financial information in case of non-listed companies will be provided as per availability

**The segmentation and the companies are subjected to modifications based on the in-depth secondary for the final deliverable

List of Figures

Figure 1: Global Artificial Cornea and Corneal Implant Market Segmentation

Figure 2: Global Artificial Cornea and Corneal Implant Market Industry Value Chain Analysis

Figure 3: Global Artificial Cornea and Corneal Implant Market Size, By Value (USD Million), 2018-2028

Figure 4: Global Artificial Cornea and Corneal Implant Market Share (%), By Type, By Value, 2018-2028

Figure 5: Global Artificial Cornea and Corneal Implant Market Share (%), By Transplant Type, By Value, 2018-2028

Figure 6: Global Artificial Cornea and Corneal Implant Market Share (%), By Disease Indication, By Value, 2018-2028

Figure 7: Global Artificial Cornea and Corneal Implant Market Share (%), By End-User, By Value, 2018-2028

Figure 8: Global Artificial Cornea and Corneal Implant Market Share (%), By Region, By Value, 2018-2028

Figure 9: North America Artificial Cornea and Corneal Implant Market Size, By Value (USD Million), 2018-2028

Figure 10: North America Artificial Cornea and Corneal Implant Market Share (%), By Type, By Value, 2018-2028

Figure 11: North America Artificial Cornea and Corneal Implant Market Share (%), By Transplant Type, By Value, 2018-2028

Figure 12: North America Artificial Cornea and Corneal Implant Market Share (%), By Disease Indication, By Value, 2018-2028

Figure 13: North America Artificial Cornea and Corneal Implant Market Share (%), By End-User, By Value, 2018-2028

Figure 14: North America Artificial Cornea and Corneal Implant Market Share (%), By Country, By Value, 2018-2028    

Figure 15: Europe Artificial Cornea and Corneal Implant Market Size, By Value (USD Million), 2018-2028

Figure 16: Europe Artificial Cornea and Corneal Implant Market Share (%), By Type, By Value, 2018-2028

Figure 17: Europe Artificial Cornea and Corneal Implant Market Share (%), By Transplant Type, By Value, 2018-2028

Figure 18: Europe Artificial Cornea and Corneal Implant Market Share (%), By Disease Indication, By Value, 2018-2028

Figure 19: Europe Artificial Cornea and Corneal Implant Market Share (%), By End-User, By Value, 2018-2028

Figure 20: Europe Artificial Cornea and Corneal Implant Market Share (%), By Country, By Value, 2018-2028

Figure 21: The Asia-Pacific Artificial Cornea and Corneal Implant Market Size, By Value (USD Million), 2018-2028

Figure 22: The Asia-Pacific Artificial Cornea and Corneal Implant Market Share (%), By Type, By Value, 2018-2028

Figure 23: The Asia-Pacific Artificial Cornea and Corneal Implant Market Share (%), By Transplant Type, By Value, 2018-2028

Figure 24: The Asia-Pacific Artificial Cornea and Corneal Implant Market Share (%), By Disease Indication, By Value, 2018-2028 

Figure 25: The Asia-Pacific Artificial Cornea and Corneal Implant Market Share (%), By End-User, By Value, 2018-2028 

Figure 26: The Asia-Pacific Artificial Cornea and Corneal Implant Market Share (%), By Country, By Value, 2018-2028

Figure 27: Latin America Artificial Cornea and Corneal Implant Market Size, By Value (USD Million), 2018-2028

Figure 28: Latin America Artificial Cornea and Corneal Implant Market Share (%), By Type, By Value, 2018-2028

Figure 29: Latin America Artificial Cornea and Corneal Implant Market Share (%), By Transplant Type, By Value, 2018-2028

Figure 30: Latin America Artificial Cornea and Corneal Implant Market Share (%), By Disease Indication, By Value, 2018-2028

Figure 31: Latin America Artificial Cornea and Corneal Implant Market Share (%), By End-User, By Value, 2018-2028

Figure 32: Latin America Artificial Cornea and Corneal Implant Market Share (%), By Country, By Value, 2018-2028

Figure 33: The Middle East & Africa Artificial Cornea and Corneal Implant Market Size, By Value (USD Million), 2018-2028

Figure 34: The Middle East & Africa Artificial Cornea and Corneal Implant Market Share (%), By Type, By Value, 2018-2028

Figure 35: The Middle East & Africa Artificial Cornea and Corneal Implant Market Share (%), By Transplant Type, By Value, 2018-2028

Figure 36: The Middle East & Africa Artificial Cornea and Corneal Implant Market Share (%), By Disease Indication, By Value, 2018-2028

Figure 37: The Middle East & Africa Artificial Cornea and Corneal Implant Market Share (%), By End-User, By Value, 2018-2028

Figure 38: The Middle East & Africa Artificial Cornea and Corneal Implant Market Share (%), By Country, By Value, 2018-2028

Figure 39: Global Artificial Cornea and Corneal Implant Market Share Analysis, 2021

List of Tables

Table 1: Global Artificial Cornea and Corneal Implant Market Size, By Type, By Value (USD Million), 2018-2028

Table 2: Global Artificial Cornea and Corneal Implant Market Size, By Transplant Type, By Value (USD Million), 2018-2028

Table 3: Global Artificial Cornea and Corneal Implant Market Size, By Disease Indication, By Value (USD Million), 2018-2028

Table 4: Global Artificial Cornea and Corneal Implant Market Size, By End-User, By Value (USD Million), 2018-2028

Table 5: Global Artificial Cornea and Corneal Implant Market Size. By Region, By Value (USD Million), 2018-2028

Table 6: North America Artificial Cornea and Corneal Implant Market Size, By Type, By Value (USD Million), 2018-2028

Table 7: North America Artificial Cornea and Corneal Implant Market Size, By Transplant Type, By Value (USD Million), 2018-2028

Table 8: North America Artificial Cornea and Corneal Implant Market Size, By Disease Indication, By Value (USD Million), 2018-2028

Table 9: North America Artificial Cornea and Corneal Implant Market Size, By End-User, By Value (USD Million), 2018-2028

Table 10: North America Artificial Cornea and Corneal Implant Market Size (USD Million), By Country, By Value 2018-2028 

Table 11: Europe Artificial Cornea and Corneal Implant Market Size, By Type, By Value (USD Million), By Value 2018-2028

Table 12: Europe Artificial Cornea and Corneal Implant Market Size, By Transplant Type, By Value (USD Million), By Value 2018-2028

Table 13: Europe Artificial Cornea and Corneal Implant Market Size, By Disease Indication, By Value (USD Million), By Value 2018-2028

Table 14: Europe Artificial Cornea and Corneal Implant Market Size, By End-User, By Value (USD Million), By Value 2018-2028

Table 15: 40 Europe Artificial Cornea and Corneal Implant Market Size (USD Million), By Country, By Value 2018-2028

Table 16: The Asia-Pacific Artificial Cornea and Corneal Implant Market Size, By Type, By Value (USD Million), By Value 2018-2028

Table 17: The Asia-Pacific Artificial Cornea and Corneal Implant Market Size (USD Million), By Type, By Value 2018-2028

Table 18: The Asia-Pacific Artificial Cornea and Corneal Implant Market Size (USD Million), By Transplant Type, By Value 2018-2028

Table 19: The Asia-Pacific Artificial Cornea and Corneal Implant Market Size (USD Million), By Disease Indication, By Value 2018-2028

Table 20: The Asia-Pacific Artificial Cornea and Corneal Implant Market Size (USD Million), By End-User, By Value 2018-2028

Table 21: The Asia-Pacific Artificial Cornea and Corneal Implant Market Size (USD Million), By Country, By Value 2018-2028

Table 22: Latin America Artificial Cornea and Corneal Implant Market Size, By Type, By Value (USD Million), By Value 2018-2028

Table 23: Latin America Artificial Cornea and Corneal Implant Market Size, By Transplant Type, By Value (USD Million), 2018-2028

Table 24: Latin America Artificial Cornea and Corneal Implant Market Size, By Disease Indication, By Value (USD Million), 2018-2028

Table 25: Latin America Artificial Cornea and Corneal Implant Market Size, By End-User, By Value (USD Million), 2018-2028

Table 26: Latin America Artificial Cornea and Corneal Implant Market Size (USD Million), By Country, By Value 2018-2028  

Table 27: The Middle East & Africa Artificial Cornea and Corneal Implant Market Size, By Type, By Value (USD Million), 2018-2028

Table 28: The Middle East & Africa Artificial Cornea and Corneal Implant Market Size, By Transplant Type, By Value (USD Million), 2018-2028

Table 29: The Middle East & Africa Artificial Cornea and Corneal Implant Market Size, By Disease Indication, By Value (USD Million), 2018-2028

Table 30: The Middle East & Africa Artificial Cornea and Corneal Implant Market Size, By End-User, By Value (USD Million), 2018-2028

Table 31: The Middle East & Africa Artificial Cornea and Corneal Implant Market Size (USD Million), By Country, By Value 2018-2028 

Table 32:  List of Key Players and Their Offerings

Table 33:  Competitive Benchmarking, by Operating Parameters

Table 34        AJL Ophthalmic Company Overview

Table 35        AJL Ophthalmic Financial Overview

Table 36        CorneaGen Inc Company Overview

Table 37        CorneaGen Inc Financial Overview

Table 38        Addition Technology Inc Company Overview

Table 39        Addition Technology Inc Financial Overview

Table 40        LinkoCare Life Science AB Company Overview

Table 41        LinkoCare Life Science AB Financial Overview

Table 42        Presbia Plc Company Overview

Table 43        Presbia Plc Financial Overview

Table 44        Mediphacos Company Overview

Table 45        Mediphacos Financial Overview

Table 46        Aurolab Company Overview

Table 47        Aurolab Financial Overview

Table 48        Cornea Biosciences Company Overview

Table 49        Cornea Biosciences Financial Overview

Table 50        Dioptex GmbH Company Overview

Table 51        Dioptex GmbH Financial Overview

Table 52        EyeYon Medical Company Overview

Table 53        EyeYon Medical Financial Overview

Table 54        Massachusetts Eye and Ear Company Overview

Table 55        Massachusetts Eye and Ear Financial Overview

Table 56        Florida Lions Eye Bank Company Overview

Table 57        Florida Lions Eye Bank Financial Overview