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Recombinant Cell Culture Supplements Market

Recombinant Cell Culture Supplements Market

Recombinant Cell Culture Supplements Market - Global Size, Share, Trend Analysis, Opportunity and Forecast Report, 2018–2028, Segmented By Products (Recombinant Growth Factors, Recombinant Insulin, Recombinant Albumin, Recombinant Transferrin, Recombinant Trypsin, Recombinant Aprotinin, Recombinant Lysozyme, and Others); By Application (Stem Cell and Regenerative Medicine (Stem Cell Therapy, Cell Therapy, Gene Therapy), Bio-Production (Monoclonal Antibodies, Recombinant Proteins, Vaccines, Hormones, Other Biological Products), and Academic and Research); By Expression System (Mammalian, E. Coli, Yeast, and Others); By Region (North America, Europe, Asia-Pacific, Latin America, Middle East & Africa)

  • Published Date: August 2022
  • Report ID: BWC22321
  • Available Format: PDF
  • Page: 273

Report Overview

Global Recombinant Cell Culture Supplements Market is growing due to the increasing investment in life sciences research and development coupled with the rising demand for cell culture supplements. The increased preference and use of animal-free supplements is also fueling the growth of the recombinant cell culture supplements market.

Global Recombinant Cell Culture Supplements Market - Industry Trends & Forecast Report 2028

Global recombinant cell culture supplements market was worth USD 309.3 million in 2021 and is projected to reach USD 702.5 million by the year 2028, exhibiting a CAGR of 12.5% during the forecast period. The rapid expansion of the market is predominantly due to increasing investment in life sciences research and development to combat the advent of novel viruses, fungi, and bacteria-causing diseases. It is also coupled with the rising demand for cell culture supplements for developing recombinant proteins, vaccines, diagnostic reagents, advanced therapies, and biotherapeutics and biopharmaceuticals. Moreover, the vast applications and advantages of the novel biotherapeutics and biopharmaceuticals over traditional animal-derived supplements is driving the growth of the global recombinant cell culture supplements market during the forecast period 2022-2028

Recombinant Cell Culture Supplements Market

Recombinant Cell Culture Supplements - Overview

Cell culture is the process of cultivating cells in in-vitro conditions for stem cell therapy, gene therapy, bioproduction of vaccines, monoclonal antibodies, hormones, and academic and research purposes. It uses supplements or growth factors that drive the differentiation into specific cell types. The augment of recombinant products has revolutionized the research approach in developing therapeutics, as these products are cost-effective and highly efficacious. There are various types of recombinant cell culture supplements such as recombinant growth factors, recombinant insulin, recombinant albumin, recombinant transferrin, recombinant trypsin, recombinant aprotinin, recombinant lysozyme, etc. These cell culture supplements boost productivity, regulate cell growth conditions and maintain healthy differentiation of cells.

Global Recombinant Cell Culture Supplements Market Forecast and Trends

Growth Drivers

Increasing Investment in Life Sciences Research and Development

Recombinant cell culture supplements are essential for the manufacturing and development of therapeutics and biopharmaceuticals. As these products have improved potency, specificity, safety, stability, and solubility, they are extensively used in life sciences research and development. The prominent players in this market are investing in this sector to innovate and expand their businesses. Manufacturers are focusing on expanding production capacity to gain significant market share. For example, in May 2022, FUJIFILM Irvine Scientific's new bioprocessing innovation and collaboration center in China became operational. They produced a variety of vaccines, advanced therapies, and biotherapeutic drugs with the help of local resources in China and optimized cell culture media. In 2018, GE Healthcare decided to increase the annual production capacity for cell culture media & supplements. Therefore, these companies' increasing investments and expansion of manufacturing capacity to create novel drug designs and treatment strategies are fueling the market growth.

Increased Use of Animal-Free Supplements

People have become very aware of the exploitation of animals and nowadays opt for animal-free products. The same is the case with recombinant cell culture supplements. Manufacturers are focusing on the production and development of animal-free products due to increased demand. Animal-free recombinant cell culture supplements are free from all animal components, serum, endotoxin, and endogenous mammalian contamination. A variety of companies manufacture animal-free growth factors, such as Peprotech, Applied Biological Materials Inc., Cell Application Inc., Gemini Bio Products, AMS Biotechnology (Europe) Limited, among others. Moreover, animal-free recombinant cell culture supplements are gaining popularity as they are manufactured using an all-human production system and also eliminate the risk of contamination of the cell culture media. The increased usage of animal-free supplements is expected to boost the growth of the market in the forecast period.

Restraints

Challenging Manufacturing Process

Although various approaches and techniques can be used to grow cell cultures, most of them face reproducibility issues due to biological variation between generations of cells. Maintaining the cell culture parameters like oxygen level, carbon dioxide level, osmotic pressure, nutrient supply, pH, temperature, and humidity is essential for the cultivation of healthy cells. This is done with the help of an incubator. To protect the cell culture from non-living contaminants, such as impurities in media, sera, supplements, water, and endotoxins and leachables, researchers use laboratory-grade water and endotoxin-test certified media, sera, supplements, and consumables. Misidentification of cell lines and viability of the cells are other key challenges faced by scientists.

Impact of COVID-19 on Global Recombinant Cell Culture Supplements Market

Like any other market, the global recombinant cell culture supplements market was also impacted during the Covid-19 pandemic. In the initial phase of the pandemic, worldwide lockdowns were imposed on the majority of countries. This compelled the manufacturers to scale down and also hampered the ongoing research and clinical development of various biopharmaceutical products. Due to the provision of research grants, the focus shifted to developing a Covid vaccine to combat the SARS-CoV-2. Moreover, the demand for research and stem cell research also increased. In the later phases of the pandemic, the government's emphasis shifted to building a robust supply chain for the transportation of Covid test kits, diagnostics, drugs, vaccines, and recombinant supplements. Thus, the recombinant cell culture supplement-producing companies maintained their financial position as their sales resumed soon.

Global Recombinant Cell Culture Supplements Market - By Application

Based on application, the global recombinant cell culture supplements market is segmented into stem cell and regenerative medicine (stem cell therapy, cell therapy, gene therapy), bio-production (monoclonal antibodies, recombinant proteins, vaccines, hormones, other biological products), and academic and research. Amidst the segmentation, the stem cell and regenerative medicine segment accounted for the largest market share of 47.95% in 2021. On the other hand, bio-production segment is estimated to expand at the highest rate because of the development of novel drugs, treatments, and technologies. Biopharmaceutical manufacturers are engaged in designing of novel technologies like upgraded expression systems, better process monitoring implements, cell line engineering, recombinant cell cultures methodology.

Global Recombinant Cell Culture Supplements Market - By Region

Based on regions, the global recombinant cell culture supplements market has been segmented into five categories- North America, Europe, Asia-Pacific, Latin America, Middle East, and Africa. Amidst the segmentation, North America dominated the global Recombinant Cell Culture Supplements market share in 2021 due to the availability of appropriate technology and sufficient funding. On the other hand, Europe is estimated to grow at the highest rate due to a large number of recombinant cell culture supplement products and manufacturing units, biopharmaceutical organizations and research institutes, and increased government funds for cell science research organizations.

Competitive Landscape

The key players operating in global recombinant cell culture supplements market are Thermo Fisher Scientific Inc., Merck KGaA, Becton, Dickinson and Company, Hi-Media Laboratories, Sartorius AG, InVitro, SeraCare Life Sciences Inc., GE Healthcare, Novozymes A/S, Advanced Biotechnologies Inc., Lonza, STEMCELL Technologies Inc., PeproTech Inc., Sino Biological Inc.,      FUJIFILM Irvine Scientific, Evercyte GmbH, Kingfisher Biotech Inc. Various key marketing strategies like alliances, agreements, mergers, and and partnerships are essential to expanding the company and keeping up with the competition. For example, in December 2019, Sartorius AG acquired a 50% stake in Biological Industries to expand its cell culture media offering and complement its existing product portfolio. Moreover, they planned to acquire 20% of the remaining shares in the next three years.

 

Recent Development

  • In June 2022, Gemini Bioproducts collaborated with Avantor to provide custom cGMP solutions. The aim was to aid biopharmaceutical companies in improving their process efficiency of hydrated solutions and cell culture media.

 

  • In March 2022, FUJIFILM Irvine Scientific acquired Shenandoah Biotechnology to gain access to the large portfolio of Shenandoah Biotechnology's recombinant proteins, cytokines, and growth factors. This acquisition also aided FUJIFILM Irvine Scientific to enhance its cell culture solutions and gain expertise in bioprocessing.

 

Scope of the Report

Attributes Details
Years Considered Historical data – 2018-2021
Base Year – 2021
Estimated Year - 2022
Forecast – 2022 – 2028
Facts Covered Revenue in USD Million
Market Coverage North America (United States, Canada), Europe (Germany, United Kingdom, France, Italy, Spain), Asia-Pacific (China, India, Australia, Japan, South Korea), Latin America (Brazil, Mexico), Middle East & Africa (Saudi Arabia, Turkey, United Arab Emirates, South Africa) 
Product Service/Segmentation By Products, By Application, By Expression System
Key Players Thermo Fisher Scientific Inc., Merck KGaA, Becton, Dickinson and Company, Hi-Media Laboratories, Sartorius AG, InVitro, SeraCare Life Sciences Inc., GE Healthcare, Novozymes A/S, Advanced Biotechnologies Inc., Lonza, STEMCELL Technologies Inc., PeproTech Inc., Sino Biological Inc.,    FUJIFILM Irvine Scientific, Evercyte GmbH, Kingfisher Biotech Inc., and other prominent players

 

By Products

  • Recombinant Growth Factors
  • Recombinant Insulin
  • Recombinant Albumin
  • Recombinant Transferrin
  • Recombinant Trypsin
  • Recombinant Aprotinin
  • Recombinant Lysozyme
  • Others

By Application

  • Stem Cell and Regenerative Medicine
    • Stem Cell Therapy
    • Cell Therapy
    • Gene Therapy
  • Bio-Production
    • Monoclonal Antibodies
    • Recombinant Proteins
    • Vaccines
    • Hormones
    • Other Biological Products
  • Academic and Research

By Expression System

  • Mammalian
  • E. Coli
  • Yeast
  • Others

By Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

  1. Research Framework
    1. Research Objective
    2. Product Overview
    3. Market Segmentation
  2. Research Methodology
    1. Qualitative Research
      1. Primary & Secondary Research
    2. Quantitative Research
    3. Market Breakdown & Data Triangulation
      1. Secondary Research
      2. Primary Research
    4. Breakdown of Primary Research Respondents, By Region
    5. Assumption & Limitation
  3. Executive Summary
  4. Global Recombinant Cell Culture Supplements Market Insights
    1. Industry Value Chain Analysis
    2. DROC Analysis
      1. Growth Drivers
      2. Restraints
      3. Opportunities
      4. Challenges
    3. Technological Advancement/Recent Development
    4. Regulatory Framework
    5. Porter’s Five Forces Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of New Entrants
      4. Threat of Substitutes
      5. Intensity of Rivalry
  5. Global Recombinant Cell Culture Supplements Market Overview
    1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
    2. Market Share & Forecast
      1. By Products
        1. Recombinant Growth Factors
        2. Recombinant Insulin
        3. Recombinant Albumin
        4. Recombinant Transferrin
        5. Recombinant Trypsin
        6. Recombinant Aprotinin
        7. Recombinant Lysozyme
        8. Others
      2. By Application
        1. Stem Cell and Regenerative Medicine
          1. Stem Cell Therapy
          2. Cell Therapy
          3. Gene Therapy
        2. Bio-Production
          1. Monoclonal Antibodies
          2. Recombinant Proteins
          3. Vaccines
          4. Hormones
          5. Other Biological Products
        3. Academic and Research Application
      3. By Expression System
        1. Mammalian
        2. E. Coli
        3. Yeast
        4. Others
      4. By Region
        1. North America
        2. Europe
        3. The Asia Pacific
        4. Latin America
        5. The Middle East and Africa
  6. North America Recombinant Cell Culture Supplements Market
    1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
    2. Market Share & Forecast
      1. By Products
      2. By Application
      3. By Expression System
      4. By Country
        1. United States
        2. Canada
  7. Europe Recombinant Cell Culture Supplements Market
    1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
    2. Market Share & Forecast
      1. By Products
      2. By Application
      3. By Expression System
      4. By Country
        1. Germany
        2. United Kingdom
        3. Italy
        4. France
        5. Spain
        6. Rest of Europe
  8. The Asia Pacific Recombinant Cell Culture Supplements Market
    1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
    2. Market Share & Forecast
      1. By Products
      2. By Application
      3. By Expression System
      4. By Country
        1. China
        2. India
        3. Japan
        4. Australia
        5. South Korea
        6. Rest of Asia Pacific
  9. Latin America Recombinant Cell Culture Supplements Market
    1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
    2. Market Share & Forecast
      1. By Products
      2. By Application
      3. By Expression System
      4. By Country
        1. Brazil
        2. Mexico
        3. Rest of Latin America
  10. The Middle East & Africa Recombinant Cell Culture Supplements Market
    1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
    2. Market Share & Forecast
      1. By Products
      2. By Application
      3. By Expression System
      4. By Country
        1. Saudi Arabia
        2. UAE
        3. Turkey
        4. South Africa
        5. Rest of Middle East & Africa
  11. Competitive Landscape
    1. List of Key Players and Their Offerings
    2. Market Share Analysis, 2028
    3. Competitive Benchmarking, By Operating Parameters
    4. Key Strategic Development (Merger, Acquisition, Partnership.)
  12. Impact of Covid-19 on Global Recombinant Cell Culture Supplements Market Industry
  13. Company Profile (Company Overview, Financial Matrix, Competitive landscape, Key Personnel, Key Competitors, Contact Address, and Strategic Outlook) **
    1. Thermo Fisher Scientific Inc.
    2. Merck KGaA
    3. Becton
    4. Dickinson and Company
    5. Hi-Media Laboratories
    6. Sartorius AG
    7. InVitro
    8. SeraCare Life Sciences Inc.
    9. GE Healthcare
    10. Novozymes A/S
    11. Advanced Biotechnologies Inc.
    12. Lonza
    13. STEMCELL Technologies Inc.
    14. PeproTech Inc.
    15. Sino Biological Inc.
    16. FUJIFILM Irvine Scientific
    17. Evercyte GmbH
    18. Kingfisher Biotech Inc.
    19. Other prominent players
  14. Key Strategic Recommendations

 

*Financial information in case of non-listed companies will be provided as per availability

**The segmentation and the companies are subjected to modifications based on in-depth secondary for the final deliverable

 

List Of Figures

 

Figure 1        Global Recombinant Cell Culture Supplements Segmentation

Figure 2        Global Recombinant Cell Culture Supplements Market Value Chain Analysis

Figure 3        Company Market Share Analysis, 2021

Figure 4        Global Recombinant Cell Culture Supplements Market Size, By Value (USD Million), 2018-2028

Figure 5        Global Recombinant Cell Culture Supplements Market Share, By Products, By Value, 2018-2028

Figure 6        Global Recombinant Cell Culture Supplements Market Share, By Application, By Value, 2018-2028

Figure 7        Global Recombinant Cell Culture Supplements Market Share, By Expression System, By Value, 2018-2028

Figure 8        Global Recombinant Cell Culture Supplements Market Share, By Region, By Value, 2018-2028

Figure 9        North America Recombinant Cell Culture Supplements Market Size, By Value (USD Million), 2018-2028

Figure 10       North America Recombinant Cell Culture Supplements Market Share, By Products, By Value, 2018-2028

Figure 11       North America Recombinant Cell Culture Supplements Market Share, By Application, By Value, 2018-2028

Figure 12       North America Recombinant Cell Culture Supplements Market Share, By Expression System, By Value, 2018-2028

Figure 13       North America Recombinant Cell Culture Supplements Market Share, By Country, By Value, 2018-2028

Figure 14       Europe Recombinant Cell Culture Supplements Market Size, By Value (USD Million), 2018-2028

Figure 15       Europe Recombinant Cell Culture Supplements Market Share, By Products, By Value, 2018-2028

Figure 16       Europe Recombinant Cell Culture Supplements Market Share, By Application, By Value, 2018-2028

Figure 17       Europe Recombinant Cell Culture Supplements Market Share, By Expression System, By Value, 2018-2028

Figure 18       Europe Recombinant Cell Culture Supplements Market Share, By Country, By Value, 2018-2028

Figure 19       The Asia-Pacific Recombinant Cell Culture Supplements Market Size, By Value (USD Million), 2018-2028

Figure 20       The Asia-Pacific Recombinant Cell Culture Supplements Market Share, By Products, By Value, 2018-2028

Figure 21       The Asia-Pacific Recombinant Cell Culture Supplements Market Share, By Application, By Value, 2018-2028

Figure 22       The Asia-Pacific Recombinant Cell Culture Supplements Market Share, By Expression System, By Value, 2018-2028

Figure 23       The Asia-Pacific Recombinant Cell Culture Supplements Market Share, By Country, By Value, 2018-2028

Figure 24       Latin America Recombinant Cell Culture Supplements Market Size, By Value (USD Million), 2018-2028

Figure 25       Latin America Recombinant Cell Culture Supplements Market Share, By Products, By Value, 2018-2028

Figure 26       Latin America Recombinant Cell Culture Supplements Market Share, By Application, By Value, 2018-2028

Figure 27       Latin America Recombinant Cell Culture Supplements Market Share, By Expression System, By Value, 2018-2028

Figure 28       Latin America Recombinant Cell Culture Supplements Market Share, By Country, By Value, 2018-2028

Figure 29       The Middle East & Africa Recombinant Cell Culture Supplements Market Size, By Value (USD Million), 2018-2028

Figure 30       The Middle East & Africa Recombinant Cell Culture Supplements Market Share, By Products, By Value, 2018-2028

Figure 31       The Middle East & Africa Recombinant Cell Culture Supplements Market Share, By Application, By Value, 2018-2028

Figure 32       The Middle East & Africa Recombinant Cell Culture Supplements Market Share, By Expression System, By Value, 2018-2028

Figure 33       The Middle East & Africa Recombinant Cell Culture Supplements Market Share, By Country, By Value, 2018-2028

 

List Of Tables

 

Table 1         Global Recombinant Cell Culture Supplements Market Size, By Products, By Value, 2018-2028

Table 2         Global Recombinant Cell Culture Supplements Market Size, By Application, By Value, 2018-2028

Table 3         Global Recombinant Cell Culture Supplements Market Size, By Expression System, By Value, 2018-2028

Table 4         Global Recombinant Cell Culture Supplements Market Size, By Region, By Value, 2018-2028

Table 5         North America Recombinant Cell Culture Supplements Market Size, By Products, By Value, 2018-2028

Table 6         North America Recombinant Cell Culture Supplements Market Size, By Application, By Value, 2018-2028

Table 7         North America Recombinant Cell Culture Supplements Market Size, By Expression System, By Value, 2018-2028

Table 8         North America Recombinant Cell Culture Supplements Market Size, By Country, By Value, 2018-2028

Table 9         Europe Recombinant Cell Culture Supplements Market Size, By Products, By Value, 2018-2028

Table 10        Europe Recombinant Cell Culture Supplements Market Size, By Application, By Value, 2018-2028

Table 11        Europe Recombinant Cell Culture Supplements Market Size, By Expression System, By Value, 2018-2028

Table 12        Europe Recombinant Cell Culture Supplements Market Size, By Country, By Value, 2018-2028

Table 13        The Asia-Pacific Recombinant Cell Culture Supplements Market Size, By Products, By Value, 2018-2028

Table 14        The Asia-Pacific Recombinant Cell Culture Supplements Market Size, By Application, By Value, 2018-2028

Table 15        The Asia-Pacific Recombinant Cell Culture Supplements Market Size, By Expression System, By Value, 2018-2028

Table 16        The Asia-Pacific Recombinant Cell Culture Supplements Market Size, By Country, By Value, 2018-2028

Table 17        Latin America Recombinant Cell Culture Supplements Market Size, By Products, By Value, 2018-2028

Table 18        Latin America Recombinant Cell Culture Supplements Market Size, By Application, By Value, 2018-2028

Table 19        Latin America Recombinant Cell Culture Supplements Market Size, By Expression System, By Value, 2018-2028

Table 20        Latin America Recombinant Cell Culture Supplements Market Size, By Country, By Value, 2018-2028

Table 21        The Middle East & Africa Recombinant Cell Culture Supplements Market Size, By Products, By Value, 2018-2028

Table 22        The Middle East & Africa Recombinant Cell Culture Supplements Market Size, By Application, By Value, 2018-2028

Table 23        The Middle East & Africa Recombinant Cell Culture Supplements Market Size, By Expression System, By Value, 2018-2028

Table 24        The Middle East & Africa Recombinant Cell Culture Supplements Market Size, By Country, By Value, 2018-2028

Table 25        Thermo Fisher Scientific Inc. Company Overview

Table 26        Thermo Fisher Scientific Inc. Financial Overview

Table 27        Merck KGaA Company Overview

Table 28        Merck KGaA Financial Overview

Table 29        Becton Company Overview

Table 30        Becton Financial Overview

Table 31        Dickinson and Company Company Overview

Table 32        Dickinson and Company Financial Overview

Table 33        Hi-Media Laboratories Company Overview

Table 34        Hi-Media Laboratories Financial Overview

Table 35        Sartorius AG Company Overview

Table 36        Sartorius AG Financial Overview

Table 37        InVitro Company Overview

Table 38        InVitro Financial Overview

Table 39        SeraCare Life Sciences Inc. Company Overview

Table 40        SeraCare Life Sciences Inc. Financial Overview

Table 41        GE Healthcare Company Overview

Table 42        GE Healthcare Financial Overview

Table 43        Novozymes A/S Company Overview

Table 44        Novozymes A/S Financial Overview

Table 45        Advanced Biotechnologies Inc. Company Overview

Table 46        Advanced Biotechnologies Inc. Financial Overview

Table 47        Lonza Company Overview

Table 48        Lonza Financial Overview

Table 49        STEMCELL Technologies Inc. Company Overview

Table 50        STEMCELL Technologies Inc. Financial Overview

Table 51        PeproTech Inc. Company Overview

Table 52        PeproTech Inc. Financial Overview

Table 53        Sino Biological Inc. Company Overview

Table 54        Sino Biological Inc. Financial Overview

Table 55        FUJIFILM Irvine Scientific Company Overview

Table 56        FUJIFILM Irvine Scientific Financial Overview

Table 57        Evercyte GmbH Company Overview

Table 58        Evercyte GmbH Financial Overview

Table 59        Kingfisher Biotech Inc. Company Overview

Table 60        Kingfisher Biotech Inc. Financial Overview

Market Segmentation

By Products

  • Recombinant Growth Factors
  • Recombinant Insulin
  • Recombinant Albumin
  • Recombinant Transferrin
  • Recombinant Trypsin
  • Recombinant Aprotinin
  • Recombinant Lysozyme
  • Others

By Application

  • Stem Cell and Regenerative Medicine
    • Stem Cell Therapy
    • Cell Therapy
    • Gene Therapy
  • Bio-Production
    • Monoclonal Antibodies
    • Recombinant Proteins
    • Vaccines
    • Hormones
    • Other Biological Products
  • Academic and Research

By Expression System

  • Mammalian
  • E. Coli
  • Yeast
  • Others

By Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa
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